diff --git a/src/bin/chrome-devtools-mcp-cli-options.ts b/src/bin/chrome-devtools-mcp-cli-options.ts
index 3cfbacac0..6619d60b0 100644
--- a/src/bin/chrome-devtools-mcp-cli-options.ts
+++ b/src/bin/chrome-devtools-mcp-cli-options.ts
@@ -7,6 +7,17 @@
 import type {YargsOptions} from '../third_party/index.js';
 import {yargs, hideBin} from '../third_party/index.js';
 
+/**
+ * On macOS, Node.js `dns.lookup('localhost')` non-deterministically resolves
+ * to `::1` (IPv6) or `127.0.0.1` (IPv4) depending on network state. Chrome's
+ * debug port typically binds only one address family, causing intermittent
+ * connection failures. This function replaces `localhost` with `127.0.0.1`
+ * to match Chrome's default binding while preserving the original URL format.
+ */
+function resolveLocalhostToIPv4(url: string): string {
+  return url.replace(/\/\/localhost([:/])/i, '//127.0.0.1$1');
+}
+
 export const cliOptions = {
   autoConnect: {
     type: 'boolean',
@@ -36,7 +47,7 @@ export const cliOptions = {
       } catch {
         throw new Error(`Provided browserUrl ${url} is not valid URL.`);
       }
-      return url;
+      return resolveLocalhostToIPv4(url);
     },
   },
   wsEndpoint: {
@@ -56,7 +67,7 @@ export const cliOptions = {
             `Provided wsEndpoint ${url} must use ws:// or wss:// protocol.`,
           );
         }
-        return url;
+        return resolveLocalhostToIPv4(url);
       } catch (error) {
         if ((error as Error).message.includes('ws://')) {
           throw error;
diff --git a/tests/cli.test.ts b/tests/cli.test.ts
index b18a4532f..8fee3dc15 100644
--- a/tests/cli.test.ts
+++ b/tests/cli.test.ts
@@ -43,17 +43,58 @@ describe('cli args parsing', () => {
       '--browserUrl',
       'http://localhost:3000',
     ]);
+    // localhost is resolved to 127.0.0.1 to avoid IPv6 resolution issues
     assert.deepStrictEqual(args, {
       ...defaultArgs,
       _: [],
       headless: false,
       $0: 'npx chrome-devtools-mcp@latest',
-      'browser-url': 'http://localhost:3000',
-      browserUrl: 'http://localhost:3000',
-      u: 'http://localhost:3000',
+      'browser-url': 'http://127.0.0.1:3000',
+      browserUrl: 'http://127.0.0.1:3000',
+      u: 'http://127.0.0.1:3000',
     });
   });
 
+  it('resolves localhost to 127.0.0.1 in browser url', async () => {
+    const args = parseArguments('1.0.0', [
+      'node',
+      'main.js',
+      '--browserUrl',
+      'http://localhost:9222',
+    ]);
+    assert.strictEqual(args.browserUrl, 'http://127.0.0.1:9222');
+  });
+
+  it('resolves LOCALHOST to 127.0.0.1 in browser url', async () => {
+    const args = parseArguments('1.0.0', [
+      'node',
+      'main.js',
+      '--browserUrl',
+      'http://LOCALHOST:9222',
+    ]);
+    assert.strictEqual(args.browserUrl, 'http://127.0.0.1:9222');
+  });
+
+  it('preserves explicit 127.0.0.1 in browser url', async () => {
+    const args = parseArguments('1.0.0', [
+      'node',
+      'main.js',
+      '--browserUrl',
+      'http://127.0.0.1:9222',
+    ]);
+    assert.strictEqual(args.browserUrl, 'http://127.0.0.1:9222');
+  });
+
+  it('preserves explicit [::1] in browser url', async () => {
+    const args = parseArguments('1.0.0', [
+      'node',
+      'main.js',
+      '--browserUrl',
+      'http://[::1]:9222',
+    ]);
+    assert.strictEqual(args.browserUrl, 'http://[::1]:9222');
+  });
+
   it('parses with user data dir', async () => {
     const args = parseArguments('1.0.0', [
       'node',
@@ -207,6 +248,19 @@ describe('cli args parsing', () => {
     });
   });
 
+  it('resolves localhost to 127.0.0.1 in wsEndpoint', async () => {
+    const args = parseArguments('1.0.0', [
+      'node',
+      'main.js',
+      '--wsEndpoint',
+      'ws://localhost:9222/devtools/browser/abc123',
+    ]);
+    assert.strictEqual(
+      args.wsEndpoint,
+      'ws://127.0.0.1:9222/devtools/browser/abc123',
+    );
+  });
+
   it('parses wsHeaders with valid JSON', async () => {
     const args = parseArguments('1.0.0', [
       'node',