In the past decade the ontology has added over 2,800 new terms including; 140 new terms for pediatric disease models, most notably in congenital heart disease; 124 terms for COVID-19, including diffuse alveolar damage and cytokine storm; and 32 Alzheimer’s-related terms such as amyloid isoform and brain lesion phenotypes. To improve cross-ontology integration, more than 1,500 MP-HPO mappings were created or refined using the SSSOM standard, resolving inconsistencies in labels, definitions, and logical axioms.
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