+* NGBO is built based on Open Biological and Biomedical Ontologies (OBO) Foundry principles. The basic formal ontology (BFO) is used as a top-level ontology for NGBO development. Pre-existing terms from other appropriately maintained ontologies, annotated with proper PURLs, labels, and textual and logical definitions, are imported, preventing multiple representations of the same entity. Examples Include OBI terms that describe entities involved in biomedical investigations, such as, but not limited to, material entities, processes, and protocols, through OWL import. From the ontology for biobanking (OBIB; https://github.com/biobanking/biobanking), terms to describe specimens, donors, and specimen management are imported. Information artifact ontology (IAO; https://github.com/information-artifact-ontology/IAO) is another relevant ontology used as a mid-level ontology and includes terms that describe identifiers, software solutions, and documents.
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